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Royal Jelly / Propolis

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  Royal Jelly / Propolis RJ extended the average mice lifespan by about 25% compared to the control group. Epigenetic programming (via bee propolis) makes bees and ants live many times longer. It's very interesting. ( video ) Increased RBC and Hematocrit after 6 months (+0.9%). Royal Jelly prolongs the life span of C3H/HeJ mice: correlation with reduced DNA damage, 2003 In this study, we investigate the effect of dietary Royal Jelly (RJ) on tissue DNA oxidative damage and on the life span of C3H/HeJ mice. In C3H/HeJ mice that were fed a dietary supplement of RJ for 16 weeks, the levels of 8-hydroxy-2-deoxyguanosine (8-OHdG), a marker of oxidative stress, were significantly reduced in kidney DNA and serum. Secondly, we determined the effect of dietary RJ on the life span in C3H/HeJ mice. The 50% mice survivals of intermediate- (about 6 mg/kg weight) and high-dose groups (about 60 mg/kg weight) were reached at significantly longer times than that of the control group according to the
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Alpha Lipoic Acid (ALA)

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  An organosulfur (an organic compound that contains sulfur). Potent antioxidant that is both water- and fat-soluble, which means it can work in every cell or tissue in the body.  This is unusual when compared to other antioxidants, which are typically either water- or fat-soluble.  These antioxidant properties may be linked to benefits such as lower blood sugar, reduced inflammation, improved nerve function, weight loss, and slowed skin aging. A coenzyme involved in cellular metabolism and the Krebs cycle, a series of chemical reactions used by mitochondria to transform energy from carbohydrates, fats, and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP) ( link ). ALA treatment significantly reduced  weight (WMD: -2.29 kg, 95% CI: -2.98, 1.60, P < .01)  BMI (WMD: -0.49 kg/m2 , 95% CI:-0.83,-0.15, P = .005) In patients diagnosed with metabolic diseases, significantly decreased ( link ) C-reactive protein (CRP) (SMD = − 1.52; 95% CI, − 2.25
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