A Short Summary of Antiaging Interventions
A SHORT SUMMARY OF LONGEVITY INTERVENTIONS How to select which intervention to bet on? We’ll look for the following evidence to come up with a strategy: [Longer human lifespan] Drugs/supplements/lifestyle changes that were shown to lower all cause mortality in long-running human RCTs (Randomized Clinical Trials) — the gold standard in research. Additionally, we will consider interventions that are associated with increased human longevity, though the evidence from RCTs might be still emerging. [Longer mice lifespan with some supporting evidence from humans] Drugs/supplements/lifestyle changes that extended mice lifespan with promising outcomes in short-term human RCTs (~causation) or retrospective analyses (~association). [Treat based on biomarkers] Treat high/low values in your labs and biomarkers (e.g. optimize when they aren’t in the ideal range). [Track your N=1] Don’t blindly follow statistics; make sure the drug/supplement you’re taking works for you specifically (N=1). Wa