MPN & Longevity Research
Basics of PV & MPN 2 What is Polycythemia Vera (PV)? 2 What are the most promising treatments for PV / MPN today? 3 PV Icin en ideal tedaviler 6 Science of PV 8 Current and emerging therapies 14 Phenotypes and blood markers for management of PV and MPNs 20 Molecular pathogenesis of the myeloproliferative neoplasms (2021) 22 Inflammation and Oxidation in MPNs 24 MPN ⇔ Endothelial Cell Connection 41 Mediterranean diet for MPNs 46 MPN SAF TSS (ref, 2012) 50 Prognosis with MPNs 51 Treatments for PV & MPN 58 Interferon-alpha for MPNs (Pegasys / Besremi) 58 Hydrea / Hydroxyurea 101 Jakafi / Ruxolitinib 109 Fedratinib 124 Momelotinib 125 Treatments in the Clinical Pipeline for PV & MPNs 126 Selinexor 127 Rusfertide (PTG-300) 128 Givinostat 130 Pelabresib 134 Imetelstat 137 Navitoclax 139 Idasanutlin (MDM2 Inhibitor) 143 Off-label Drugs and Supplements for PV & MPNs 145 Pioglitazone 145 Leukotriene Inhibitors (Singulai