Alpha Lipoic Acid (ALA)
An organosulfur (an organic compound that contains sulfur). Potent antioxidant that is both water- and fat-soluble, which means it can work in every cell or tissue in the body. This is unusual when compared to other antioxidants, which are typically either water- or fat-soluble. These antioxidant properties may be linked to benefits such as lower blood sugar, reduced inflammation, improved nerve function, weight loss, and slowed skin aging. A coenzyme involved in cellular metabolism and the Krebs cycle, a series of chemical reactions used by mitochondria to transform energy from carbohydrates, fats, and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP) ( link ). ALA treatment significantly reduced weight (WMD: -2.29 kg, 95% CI: -2.98, 1.60, P < .01) BMI (WMD: -0.49 kg/m2 , 95% CI:-0.83,-0.15, P = .005) In patients diagnosed with metabolic diseases, significantly decreased ( link ) C-reactive protein (CRP) (SMD = − 1.52; 95% CI, − 2.25