Fish oil
Associated with reduced symptom burden and improved well being scores in MPN. Helps with Depression: EPA is effective in the prevention of depression receiving IFN-α therapy. 66% reduction in risk of depression (p = .037) Reduces platelet aggregation, coagulation and thrombosis. Decreased the serum levels of TNF α , IL-1 β , IL-6, and nitric oxide metabolites over up to 6 months upon continuous use in one study. In hypertensives, supplementation resulted in lower SBP 2.56 mmHg (95% CI 0.58 to 4.53) and DBP 1.47 mmHg (95% CI 0.41 to 2.53). Lowers nuclear factor-kappa B (NF-κB) gene expression. Inhibited Interferon-mediated NF-κB activation and enhanced apoptotic cell death in IFN-treated cells. Improved chemotherapy tolerability and cancer patient outcomes in a meta-analysis. STAT3 Inhibitor: DHA acid inhibits the phosphorylation of STAT3 and the growth and invasion of renal cancer cells (RCC). Has JAK2 inhibiting effects: Not the strongest JAK2 inhibitor, but it does i...