Index

My Longevity Journey

An organized collection of research and insights.

Diets & Nutrition

Ketogenic Diet: A Balanced Look?

Explores the anti-inflammatory benefits of the ketogenic diet and its potential role in inhibiting cancer growth.

Mediterranean Diet

A heart-healthy eating plan that emphasizes whole, minimally processed foods.

Mediterranean Keto Diet

Discusses a hybrid approach combining the benefits of two popular dietary patterns for overall health.

What do I eat on Mediterranean Keto?

Provides practical food choices and meal ideas for following a Mediterranean-style ketogenic diet.

Vegetable and Fruit Juices

Examines the effects and mechanisms of fruit and vegetable juices on cardiovascular health.

Liquid Diet to Complement Mediterrenean Keto

Ideas for incorporating liquid nutrition into a Mediterranean keto plan, focusing on anti-inflammatory ingredients.

Supplements & Compounds

Quercetin

Investigates the potential of quercetin, a flavonoid, in the context of Polycythemia Vera and other Myeloproliferative Neoplasms.

Green tea for heart health and longevity

Details research on how green tea consumption can improve endothelial function and other markers of cardiovascular health.

CoQ10

An overview of Coenzyme Q10's role in the body and its connection to degenerative disorders and longevity.

L-Carnitine

Explores L-Carnitine's function in mitochondrial health and cellular energy production.

L Arginine

A look into supplements and drugs aimed at improving the flexibility of red blood cells.

Royal Jelly / Propolis

Discusses the impact of royal jelly on mice lifespan and its potential epigenetic programming effects.

Alpha Lipoic Acid (ALA)

A look at ALA, a potent antioxidant that is both water- and fat-soluble, and its broad effects.

Curcumin to Inhibit JAK2

Highlights curcumin as a promising natural compound for inhibiting the JAK2/STAT3 pathway.

Green Tea for MPNs

Explores how daily consumption of green tea or its extract, EGCG, may inhibit the JAK/STAT pathway in MPNs.

Taurine

Covers the role of taurine in extending lifespan in mice and its connection to reducing cellular senescence.

Multivitamin

Presents findings from a meta-analysis on the effects of multivitamins on all-cause mortality.

Vitamin K2

Discusses a pilot study on a vitamin K2 analog and its potential to reduce recurrence rates of hepatocellular carcinoma.

Alpha Ketoglutarate (AKG)

An overview of AKG as a Krebs cycle intermediate and its functions as a cofactor for various enzymes.

Natto / Spermidine

Examines the effects of spermidine from natto on lifespan extension in mice and its association with reduced mortality.

Medicinal Mushrooms

Lists various mushrooms that have shown effectiveness against cancer, such as Reishi and Turkey Tail.

NAD+ Boosters

Discusses Niacin and its effects on reducing liver fat and visceral fat in a human study.

Sesame

Highlights a study where sesame oil beneficially affected several cardiometabolic indices.

Hibiscus

Explains how hibiscus, rich in anthocyanins, can lower blood pressure in hypertensive adults.

Vitamin E

Discusses the relationship between Vitamin E dosage and all-cause mortality based on RCTs.

Selenium / Brazil Nuts

Presents findings on decreased all-cause mortality risk with antioxidant mixtures containing selenium.

Ginger

Outlines the benefits of ginger for patients with Type 2 Diabetes, including improved insulin resistance.

Cocoa

Details a human RCT where cocoa flavanols resulted in a reduction in all-cause mortality.

Vitamin C

A brief note on the widely known vitamin and its various health benefits.

Cruciferous Vegetables

Information about the health benefits derived from this family of vegetables.

Garlic

An overview of the health properties associated with garlic consumption.

Aspirin

General information about the common uses and effects of aspirin.

Pharmaceuticals & Therapies

Flubendazole and Other Microtubule Disrupters

Details on Flubendazole, an anthelmintic, and its chemical relation to Mebendazole.

Ezetimibe Lipid-Lowering Therapy Beyond Statins

A meta-analysis of ezetimibe's effects on mortality and cardiovascular outcomes.

Cimetidine (H2 Antihistamines)

Discusses the anti-proliferative effects of this first-generation H2 receptor antagonist on cancer cells.

Bisphosphonates

Information on the most widely used medications for osteoporosis and fracture prevention.

Ibuprofen

Summarizes research on ibuprofen's lifespan extension effects in various species, including yeast and nematodes.

Colchicine

Explains the use of Colchicine for treating gout and its mechanism of reducing inflammation.

Ezetimibe

Details how ezetimibe works to lower cholesterol levels in the body through a unique mechanism.

Pioglitazone

An overview of Pioglitazone and other Thiazolidinediones as PPARγ activators.

Leukotriene Inhibitors

A summary of how these medications block inflammatory leukotrienes to alleviate various conditions.

Testosterone Replacement Therapy (TRT)

Describes TRT as a highly impactful FDA-approved therapy for life extension in hypogonadal men.

H1-Antihistamines / Loratadine (Claritin) / Desloratadine

A brief overview of this class of antihistamines and their common uses.

Antibiotics

General information regarding the use and function of antibiotics.

Clostridium butyricum (CBM588 / Probiotics) and Sodium Butyrate

Information about this probiotic strain and its production of butyrate.

Metformin

A brief overview of Metformin, a widely used medication for type 2 diabetes.

Interferon

Basic information about the role and function of interferons in the body.

Acarbose

A short description of Acarbose and its mechanism of action.

Health Conditions & Processes

Importance of Maintaining Proteolysis as We Get Older

Discusses why the enzymatic breakdown of proteins is crucial for cellular health as we age.

RNA: From Messenger to Master Regulator of Life

A reevaluation of RNA's role in biological processes, moving beyond its traditional messenger function.

Plaque Reduction / CVD

An overview of interventions like statins that can lead to atherosclerotic plaque regression.

PAI-1

Explains the link between elevated PAI-1 levels and adverse health outcomes, and how Nattokinase may help.

MPN & Longevity Research

An introduction to Polycythemia Vera (PV) and other Myeloproliferative Neoplasms (MPNs).

What are the best treatments for PV today?

A review of current promising treatments for Polycythemia Vera, including phlebotomy and aspirin.

Inflammation and Oxidation in MPNs

Discusses the role of proinflammatory cytokines like IL-1β and TNF-α in Myeloproliferative Neoplasms.

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